Wednesday, April 30, 2008

Louis Pasteur(1822-1895)-The scientist I adore most!!!

LOUIS PASTEUR(1822-1895)

Louis Pasteur (December 27 1822 – September 28, 1895) was a French chemist and microbiologist best known for his remarkable breakthroughs in the causes and prevention of disease. His experiments supported the germ theory of disease, also reducing mortality from puerperal fever (childbed), and he created the first vaccine for rabies. He was best known to the general public for inventing a method to stop milk and wine from causing sickness - this process came to be called pasteurization. He is regarded as one of the three main founders of microbiology, together with Ferdinand Cohn and Robert Koch. He also made many discoveries in the field of chemistry, most notably the asymmetry of crystals.[1] He is buried beneath the Institut Pasteur, an incredibly rare honor in France, where being buried in a cemetery is mandatory save for the fewer than 300 "Great Men" who are entombed in the Panthéon.

Pasteur's achievements seem wildly diverse at first glance, but a more in-depth look at the evolution of his career indicates that there is a logical order to his discoveries. He is revered for possessing the most important qualities of a scientist: the ability to survey all the known data and link the data for all possible hypotheses, the patience and drive to conduct experiments under strictly controlled conditions, and the brilliance to uncover the road to the solution from the results.
On the discipline of rigid and strict experimental tests he commented, "Imagination should give wings to our thoughts but we always need decisive experimental proof, and when the moment comes to draw conclusions and to interpret the gathered observations, imagination must be checked and documented by the factual results of the experiment."


In 1854 Pasteur was appointed professor of chemistry at the University of Lille. Part of the remit of the faculty of sciences was to find solutions to the practical problems of local industries, particularly the manufacture of alcoholic drinks. He was able to demonstrate that organisms such as bacteria were responsible for souring wine and beer (he later extended his studies to prove that milk was the same), and that the bacteria could be removed by boiling and then cooling the liquid. This process is now called pasteurisation.


Louis Pasteur - experimented on animals to prove theory thatgermscause disease and developed an anthrax vaccine

Pasteur then undertook experiments to find where these bacteria came from, and was able to prove that they were introduced from the environment. This was disputed by scientists who believed they could spontaneously generate. In 1864, the French Academy of Sciences accepted Pasteur's results. By 1865, Pasteur was director of scientific studies at the École Normale, where he had studied. He was asked to help the silk industry in southern France, where there was an epidemic amongst the silkworms. With no experience of the subject, Pasteur identified parasitic infections as the cause and advocated that only disease-free eggs should be selected. The industry was saved.
Pasteur's various investigations convinced him of the rightness of the germ theory of disease, which holds that germs attack the body from outside. Many felt that such tiny organisms as germs could not possibly kill larger ones such as humans. Pasteur now extended this theory to explain the causes of many diseases - including anthrax, cholera, TB and smallpox - and their prevention by vaccination. He is best known for his work on the development of vaccines for rabies.
In 1888, a special institute was founded in Paris for the treatment of diseases. It became known as the Institut Pasteur. Pasteur was its director until his death on 28 September 1895. He was a national hero and was given a state funeral.
references:
www.britannica.com/eb/article-9108485/Louis-Pasteur - 60k
www.bbc.co.uk/history/historic_figures/pasteur_louis.shtml